Browsing Faculty of Health Sciences by Author "Mpoya, Ayub"

Now showing items 1-8 of 8

Children’s Oxygen Administration Strategies Trial (COAST): A randomised controlled trial of high flow versus oxygen versus control in African children with severe pneumonia

Maitland, Kathryn; Kiguli, Sarah; Opoka, Robert O.; Olupot-Olupot, Peter; Engoru, Charles; Njuguna, Patricia; Bandika, Victor; Mpoya, Ayub; Bush, Andrew; Williams, Thomas N.; Grieve, Richard; Sadique, Zia; Fraser, John; Harrison, David; Rowan, Kathy (Wellcome Trust, 2018)

Background: In Africa, the clinical syndrome of pneumonia remains the leading cause of morbidity and mortality in children in the post-neonatal period. This represents a significant burden on in-patient services. The ...
Co-trimoxazole or multivitamin multimineral supplement for post-discharge outcomes after severe anaemia in African children: a randomised controlled trial

Maitland, Kathryn; Olupot-Olupot, Peter; Kiguli, Sarah; Chagaluka, George; Alaroker, Florence; Opoka, Robert O; Mpoya, Ayub; Walsh, Kevin; Engoru, Charles; Nteziyaremye, Julius; Mallewa, Machpherson; Kennedy, Neil; Nakuya, Margaret; Namayanja, Cate; Kayaga, Julianne; Nabawanuka, Eva; Sennyondo, Tonny; Aromut, Denis; Kumwenda, Felistas; Bates, Imelda; von Hensbroek, Michael Boele; Evans, Jennifer A; Uyoga, Sophie; Williams, Thomas N; Frost, Gary; George, Elizabeth C.; Gibb, Diana M.; Walker, A Sarah (Elsevier, 2019)

Background Severe anaemia is a leading cause of paediatric admission to hospital in Africa; post-discharge outcomes remain poor, with high 6-month mortality (8%) and re-admission (17%). We aimed to investigate ...
Gastroenteritis Aggressive Versus Slow Treatment For Rehydration (GASTRO). A pilot rehydration study for severe dehydration: WHO plan C versus slower rehydration

Houston, Kirsty A.; Gibb, Jack G.; Mpoya, Ayub; Obonyo, Nchafatso; Olupot-Olupot, Peter; Nakuya, Margeret; Evans, Jennifer; George, Elizabeth C.; Gibb, Diana M.; Maitland, Kathryn (Wellcome Trust, 2017)

Background: The World Health Organization (WHO) rehydration management guidelines (Plan C) for children with acute gastroenteritis (AGE) and severe dehydration are widely practiced in resource-poor settings, yet have ...
Incidence and predictors of hospital readmission in children presenting with severe anaemia in Uganda and Malawi :

Connon, Roisin; George, Elizabeth C.; Olupot-Olupot, Peter; Kiguli, Sarah; Chagaluka, George; Alaroker, Florence; Opoka, Robert O.; Mpoya, Ayub (Busitema University ; BMC Public Health, 2021)

Background: Severe anaemia (haemoglobin < 6 g/dL) is a leading cause of recurrent hospitalisation in African children. We investigated predictors of readmission in children hospitalised with severe anaemia in the TRACT ...
Modifying Intestinal Integrity and MicroBiome in Severe Malnutrition with Legume-Based Feeds (MIMBLE 2.0): protocol for a phase II refined feed and intervention trial

Walsh, Kevin; Calder, Nuala; Olupot-Olupot, Peter; Ssenyondo, Tonny; Okiror, William; Okalebo, Charles Bernard; Muhindo, Rita; Mpoya, Ayub; Holmes, Elaine; Marchesi, Julian; de Chenevarin, Gael Delamare de la Villenaise; Frost, Gary; Maitland, Kathryn (F1000Research, 2018)

Background: Changes in intestinal mucosal integrity and gut microbial balance occur in severe acute malnutrition (SAM), resulting in treatment failure and adverse clinical outcomes (gram-negative sepsis, diarrhoea and ...
Phase II trial of standard versus increased transfusion volume in Ugandan children with acute severe anemia

Olupot-Olupot, Peter; Engoru, Charles; Thompson, Jennifer; Nteziyaremye, Julius; Chebet, Martin; Ssenyondo, Tonny; Dambisya, Cornelius M.; Okuuny, Vicent; Wokulira, Ronald; Amorut, Denis; Ongodia, Paul; Mpoya, Ayub; Williams, Thomas N.; Uyoga, Sophie; Macharia, Alex; Gibb, Diana M.; Walker, A. Sarah; Maitland, Kathryn (BMC, 2018)

Background: Severe anemia (SA, hemoglobin <6 g/dl) is a leading cause of pediatric hospital admission in Africa, with significant in-hospital mortality. The underlying etiology is often infectious, but specific pathogens ...
Predicting mortality in sick African children: the FEAST Paediatric Emergency Triage (PET) Score

George, Elizabeth C.; Walker, Sarah; Kiguli, Sarah; Olupot-Olupot, Peter; Opoka, Robert O.; Engoru, Charles; Akech, Samuel; Nyeko, Richard; Mtove, George; Reyburn, Hugh; Berkley, James A.; Mpoya, Ayub; Levin, Michael; Crawley, Jane; Gibb, Diana M.; Maitland, Kathryn; Babiker, Abdel G. (BMC, 2015)

Background: Mortality in paediatric emergency care units in Africa often occurs within the first 24 h of admission and remains high. Alongside effective triage systems, a practical clinical bedside risk score to identify ...
Transfusion and Treatment of severe anaemia in African children (TRACT): a study protocol for a randomised controlled trial

Mpoya, Ayub; Olupot-Olupot, Peter; Kiguli, Sarah; Opoka, Robert O.; Engoru, Charles; Macpherson, Mallewa; Chimalizeni, Yami; Kennedy, Neil; Kyeyune, Dorothy; Wabwire, Benjamin; M’baya, Bridon; Bates, Imelda; Urban, Britta C,; van Hensbroek, Michael Boele; Heyderman, Robert; Thomason, Margaret J.; Uyoga, Sophie; Williams, Thomas N.; Gibb, Diana M.; George, Elizabeth C.; Walker, Sarah; Maitland, Kathryn (BMC, 2015)

Background: In sub-Saharan Africa, where infectious diseases and nutritional deficiencies are common, severe anaemia is a common cause of paediatric hospital admission, yet the evidence to support current treatment rec ...

Browsing Faculty of Health Sciences by Author "Mpoya, Ayub"

Browsing Faculty of Health Sciences by Author "Mpoya, Ayub"

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