Department of Pediatrics
http://hdl.handle.net/20.500.12283/328
2024-03-28T20:50:45ZSurgical Release of Gluteal Fibrosis in Children Results in Sustained Benefit at 5-Year Follow-up
http://hdl.handle.net/20.500.12283/728
Surgical Release of Gluteal Fibrosis in Children Results in Sustained Benefit at 5-Year Follow-up
Amanda, Reilly L.; Owori, Francis R; Obaikol, Ruth; Asige, Elizabeth; Aluka, Harriet; Penny, Norgrove; Sabatini, Coleen S.
Background:
Gluteal fibrosis (GF) is a fibrotic infiltration of the gluteal muscles resulting in functionally limiting contracture of the hips and is associated with injections of medications into the gluteal muscles. It has been reported in numerous countries throughout the world. This study assesses the 5-year postoperative range of motion (ROM) and functional outcomes for Ugandan children who underwent surgical release of GF.
Methods:
A retrospective cohort study of children who underwent release of GF in 2013 at Kumi Hospital in Eastern Uganda. Functional outcomes, hip ROM, and scar satisfaction data were collected for all patients residing within 40 km of the hospital.
Results:
One hundred eighteen children ages 4 to 16 at the time of surgery were treated with surgical release of GF in 2013 at Kumi Hospital. Of those 118, 89 were included in this study (79.5%). The remaining 29 were lost to follow-up or lived outside the study’s radius. Detailed preoperative ROM and functional data were available for 53 of the 89 patients. In comparison with preoperative assessment, all patients postoperatively reported ability to run normally (P<0.001), sit upright in a chair (P<0.001), sit while eating (P<0.001), and attend the entire day of school (P<0.001). Passive hip flexion (P<0.001) improved when compared with preoperative measurements. In all, 85.2% (n=75) of patients reported satisfaction with scar appearance as “ok,” “good,” or “excellent” 29.2% (n=26) of patients reported back or hip complaints.
Conclusions:
Overall, the 5-year postoperative outcomes suggest that surgical release of GF improves ROM and functional quality of life with sustained effect.
Keywords: Uganda; fibrosis surgery; gluteal fibrosis; injection injury; pediatric hip contracture; treatment outcome.
Article
2021-03-11T00:00:00ZPrevalence of Plasmodium falciparum and Intestinal Parasitemia, and Clinical Outcomes of these Co-Morbidities among Children in Kiryandongo Refugee Camp, Mid -Western Uganda
http://hdl.handle.net/20.500.12283/388
Prevalence of Plasmodium falciparum and Intestinal Parasitemia, and Clinical Outcomes of these Co-Morbidities among Children in Kiryandongo Refugee Camp, Mid -Western Uganda
Oboth, Paul
The prevalence of Plasmodium falciparum and Intestinal Parasitic Infections (IPIs) - with the corresponding disease characteristics among children remain uncertain. This study aimed at determining the prevalence and evaluation of the nature of associations of the respective infections and the clinical outcomes.
METHODS: This was a cross sectional study conducted among 476-refugee camp
schoolchildren. Kato-Katz technique was used to screen stool samples for intestinal parasites. Geimsa thick blood smear microscopy was used for malaria testing while the portable Hb calorimeter was used to measure haemoglobin concentration.
RESULTS: The overall prevalence of the mixed infections was 62.2%. Plasmodium falciparum was most prevalent of the single infections 262(55.04%) followed by Taenia spp 14 (2.9%), Schistosoma mansoni 12(2.5%), Giardia lamblia 7 (2.9%), Trichuris trichiura 2(0.4%), Hookworm 2(0.4%) and Strongyloides stercoralis 1(0.2%). The odds of developing simple or uncomplicated malaria infection or anaemia was 14 times higher in individuals with dual co-infection with; Plasmodium falciparum+Taenia spp compared to single parasitic infection (Odds = 14.13, P = 0.019). Co-infection with Plasmodium falciparum+Taenia spp was a strong predictor of Malaria and anemia. This is in agreement with studies conducted in North Western and Western Uganda, which have strongly indicated that Malaria and IPIs are risk factors for childhood anemia.
CONCLUSION: This study shows that Plasmodium falciparum and Taenia spp co-
infections is a stronger predictor of malaria and anaemia. Even when there were vivid control measures in the camp, the prevalence of malaria and anaemia remains higher than the other regions in Uganda outside restricted settlements.
2018-09-12T00:00:00Z