Abstract:
The comparative study on the anthelmintic potency of pawpaw leaf was investigated in naturally infected local indigenous goats of age group between 5-12 months which was in accordance with the study conducted by Nsereko in central Uganda that the worm burden where highest between 3-5 and 8-9 months old. The selected eight (08) samples of goats of the weight range of 10-20kg body weight was screened by picking their fiscal sample for nematodes egg count under microscope for examination of natural helminthes before exposure to extract and control which is Albendazole. The purpose of the study was to determine the efficacy of pawpaw (Cardiac papaya) leaves in the treatment of gastrointestinal nematodes in goats. The sample size of eight goats (08) were divided randomly into four treatments that was A which was exposed to 2.5% pawpaw leaves extract, B which was 10% pawpaw leaf extract, C which was 2.5% Albendazole and D which was 10% Albendazole. Treatments A and B were extracted by 98% ethanol solvent using soxhlet apparatus. The results were as follows: In all the eight (8) goats’ baseline counting, there was no significant difference in the nematodes (p value=1.0). However, there was reduction in the number of nematodes in the first drug exposure but there was no significant different in all the four study treatment and in Comparison of efficacy of pawpaw leaf extracts and Albendazole on GIT nematodes there was no significant difference between the 2.5% extract concentration and 2.5% Albendazole concentration in the reduction of nematodes in the second drug exposure. However, there was significant difference between the 10% extract and 10% Albendazole in the second drug exposure In the view of the above result, the reduction in the number of nematodes were the same in both pawpaw leaf extract and control hence there are no significant difference in the concentration in both first and second treatment hence both Albendazole and extract reduced the egg production therefore, the study allows us to affirm the use of pawpaw leaf plant extract as an alternative anthelmintic for goats and that in a farming environment, the leaves seem to be effective and are able to replace synthetic molecules to avoid the cost and the resistance observed during the repeated use of these molecules.
