Browsing Research Papers by Subject "Sepsis"

Browsing Research Papers by Subject "Sepsis"

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  • Anaemia and blood transfusion in African children presenting to hospital with severe febrile illness 
    Kiguli, Sarah; Maitland, Kathryn; George, Elizabeth C.; Olupot-Olupot, Peter; Opoka, Robert O.; Engoru, Charles; Akech, Samuel; Nyeko, Richard; Mtove, George; Reyburn, Hugh; Levin, Michael; Babiker, Abdel G.; Gibb, Diana M.; Crawley, Jane (BMC, 2015)
    Background: Severe anaemia in children is a leading cause of hospital admission and a major cause of mortality in sub-Saharan Africa, yet there are limited published data on blood transfusion in this vulnerable group. Methods: ...
  • Endotoxaemia is common in children with Plasmodium falciparum malaria 
    Olupot-Olupot, Peter; Urban, Britta C,; Jemutai, Julie; Nteziyaremye, Julius; Fanjo, Harry M.; Karanja, Henry; Karisa, Japhet; Ongodia, Paul; Bwonyo, Patrick; Gitau, Evelyn N.; Talbert, Alison; Akech, Samuel; Maitland, Kathryn (BMC, 2013)
    Background: Children presenting to hospital with recent or current Plasmodium falciparum malaria are at increased the risk of invasive bacterial disease, largely enteric gram-negative organisms (ENGO), which is associated ...
  • In search of a primary outcome for community-based newborn infection trials in Eastern Uganda: a nested cohort study within the BabyGel pilot trial 
    Mobbs, N. A.; Ditai, James; Abeso, J.; Faragher, E. B.; Carrol, E. D.; Gladstone, M.; Medina-Lara, A.; Olupot-Olupot, Peter; Weeks, A. D. (BMC, 2019)
    Background: Due to their immature immune system, neonates are at high risk of infection. This vulnerability when combined with limited resources and health education in developing countries can lead to sepsis, resulting ...
  • Lactate clearance as a prognostic marker of mortality in severely ill febrile children in East Africa 
    Aramburo, A.; Todd, Jim; George, Elizabeth C.; Kiguli, Sarah; Olupot-Olupot, Peter; Opoka, Robert O.; Engoru, Charles; Akech, Samuel; Nyeko, Richard; Mtove, George; Gibb, Diana M.; Babiker, Abdel G.; Maitland, Kathryn (BMC, 2018)
    Background: Hyperlactataemia (HL) is a biomarker of disease severity that predicts mortality in patients with sepsis and malaria. Lactate clearance (LC) during resuscitation has been shown to be a prognostic factor of ...
  • Transfusion and Treatment of severe anaemia in African children (TRACT): a study protocol for a randomised controlled trial 
    Mpoya, Ayub; Olupot-Olupot, Peter; Kiguli, Sarah; Opoka, Robert O.; Engoru, Charles; Macpherson, Mallewa; Chimalizeni, Yami; Kennedy, Neil; Kyeyune, Dorothy; Wabwire, Benjamin; M’baya, Bridon; Bates, Imelda; Urban, Britta C,; van Hensbroek, Michael Boele; Heyderman, Robert; Thomason, Margaret J.; Uyoga, Sophie; Williams, Thomas N.; Gibb, Diana M.; George, Elizabeth C.; Walker, Sarah; Maitland, Kathryn (BMC, 2015)
    Background: In sub-Saharan Africa, where infectious diseases and nutritional deficiencies are common, severe anaemia is a common cause of paediatric hospital admission, yet the evidence to support current treatment rec ...

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