Molecular epidemiology of anaplasmosis in small ruminants along a human-livestock-wildlife interface in Uganda

Show simple item record Kasozi, Keneth Iceland Welburn, Susan Christina Batiha, Gaber El-Saber Marraiki, Najat Nalumenya, David Paul Namayanja, Monica Matama, Kevin Zalwango, Kelly Katenta Matovu, Wycliff Zirintunda, Gerald Ekou, Justin Kembabazi, Stellamaris Mugasa, Claire Mack Kitibwa, Annah Tayebwa, Dickson Stuart Musinguzi, Simon Peter Mahero, Michael Ssengendo, Ibrahim Nanteza, Anne Matovu, Enock MacLeod, Ewan Thomas 2021-02-17T08:53:40Z 2021-02-17T08:53:40Z 2020
dc.description Research Article en_US
dc.description.abstract Background: Information as regards the epidemiology of the Anaplasmataceae in small ruminants in several lowand middle-income countries is scarce. Methods: In this study a total of 712 DNA samples collected from small ruminants were analyzed for Anaplasmataceae and Anaplasma ovis using the 16S rRNA and MSP4 genes respectively. Infection risk was assessed by location, sex and age of the animals and qGIS® was used to construct spatial maps. Results: The prevalence of Anaplasmataceae spp was 89.1% (95% CI: 77.5–95.9) and 79.1% (95% CI: 75.9–82.1) in ovines and caprines respectively (RR ¼ 1.1, 95% CI: 1.0–1.3); higher than those previously reported in other eastern African countries. The prevalence of A. ovis was 26.1% and 25.4% for both ovines and caprines respectively with ovines showing significantly higher levels of infection than caprines (P < 0.05). The risk of Anaplasma ovis infections was not affected by age (OR ¼ 1.2, 95% CI: 0.9–1.7) or sex (OR ¼ 1.1, 95% CI: 0.6–2.0). Small ruminants located at the forest edge ( en_US
dc.description.sponsorship a .Infection Medicine, Deanery of Biomedical Sciences, College of Medicine and Veterinary Medicine, The University of Edinburgh, 1 George Square, Edinburgh EH8 9JZ, United Kingdom b. Department of Animal Production and Management, Faculty of Agriculture and Agricultural Sciences, Busitema University Arapai Campus, Box 203 Soroti, Uganda c .School of Medicine, Kabale University, Box 317 Kabale, Uganda d. Zhejiang University-University of Edinburgh Institute, Zhejiang University School of Medicine, International Campus, 718 East Haizhou Road, Haining 314400, China e. Department of Pharmacology and Therapeutics, Faculty of Veterinary Medicine, Damanhour University, Damanhour 22511, AlBeheira, Egypt f .Department of Botany and Microbiology, College of Science, King Saud University, Riyadh 11451, Saudi Arabia g. College of Veterinary Medicine Animal Resources and Biosecurity, Makerere University, Box 7062 Kampala, Uganda h. Kampala International University Western Campus, Box 71 Bushenyi, Uganda i. Faculty of Agriculture and Environmental Sciences, Kabale University, Box 315 Kabale, Uganda j. Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, USA en_US
dc.publisher Published by Elsevier Ltd en_US
dc.relation.ispartofseries Heliyon;6 (2020) e05688
dc.subject Tick-borne diseases en_US
dc.subject Anaplasma ovis en_US
dc.subject Parasites en_US
dc.subject Small ruminants en_US
dc.subject Goats en_US
dc.subject Uganda. en_US
dc.subject Africa en_US
dc.subject Ticks en_US
dc.subject Tick resistance en_US
dc.subject Tick vaccines en_US
dc.subject Entomology en_US
dc.subject Ecosystem services en_US
dc.subject Protozoa en_US
dc.subject Polymerase chain reaction en_US
dc.subject Epidemiology en_US
dc.subject Veterinary medicine en_US
dc.subject Animal behaviour en_US
dc.subject Animal breeding en_US
dc.subject Ruminant en_US
dc.subject Agriculture en_US
dc.title Molecular epidemiology of anaplasmosis in small ruminants along a human-livestock-wildlife interface in Uganda en_US
dc.type Article en_US

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